Compare the Top Endpoint Protection Software for Startups as of April 2026

What is Endpoint Protection Software for Startups?

Endpoint protection software is a software platform that provides the solution to secure endpoints—such as laptops, desktops, smartphones, and tablets—against cyber threats and attacks. These platforms provide real-time monitoring and defense mechanisms to protect devices from malware, ransomware, phishing, and other types of threats. Endpoint protection software typically includes antivirus, anti-malware, firewall, encryption, and intrusion prevention features to prevent unauthorized access and ensure data security. It also allows for centralized management, enabling IT teams to enforce security policies, update software, and monitor the health of all devices in the network. By using endpoint protection software, organizations can safeguard their devices and networks from cyber risks while maintaining compliance with security standards. Compare and read user reviews of the best Endpoint Protection software for Startups currently available using the table below. This list is updated regularly.

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    DriveStrike

    DriveStrike

    DriveStrike

    DriveStrike is easy to use, implement and manage. With DriveStrike you can execute secure remote wipe, remote lock, and remote locate commands on any platform. Integrated drive encryption support as well as mobile device management MDM for mobile platforms. Our professional support team is always available to answer your questions and help you install our services or manage your account and devices. Protecting your data and devices has never been easier or more cost effective. If you have questions or need help understanding how best to protect your data please contact us and we will gladly answer your questions. Protect your business with a device and data protection platform that keeps all devices safe with a single solution and Dashboard. Keep your Workstations, MacBooks, iPads, Smartphones, Tablets, Laptops safe, secure, and organized.
    Starting Price: $0.99 per month
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  • 2
    ThreatLocker

    ThreatLocker

    ThreatLocker

    The ThreatLocker suite of security tools are powerful and designed so that everyone from businesses to government agencies to academic institutions can directly control exactly what applications run on their networks. We envision a future in which all organizations can chart their own course free from the influence of cybercriminals and the damage their incursions cause, and our team of veteran cybersecurity professionals created ThreatLocker to make this vision a reality. The team at ThreatLocker has been developing cybersecurity tools for decades, including programs to enhance email and content security, and this is our most innovative and ambitious cybersecurity solution yet. We developed this unique cybersecurity system because we believe that organizations should have complete control of their networks and should not have to live in fear of the next malware attack. To learn more, visit ThreatLocker.com.
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  • 3
    NinjaOne

    NinjaOne

    NinjaOne

    NinjaOne enhances endpoint protection through monitoring, patching, and software controls. Automated alerts flag suspicious behavior or unauthorized applications. Regular patching keeps devices protected from vulnerabilities. Remote commands allow technicians to remediate threats instantly. Backup features add an extra layer of security against ransomware. Centralized reporting provides insights into endpoint security posture. NinjaOne ensures endpoints remain safe and compliant.
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  • 4
    Heimdal Endpoint Detection and Response (EDR)
    Heimdal® Endpoint Detection and Response is our proprietary multi-solution service providing unique prevention, threat-hunting, and remediation capabilities. It combines some of the most advanced threat-hunting technologies: - Next-Gen Antivirus - Privileged Access Management - Application Control - Ransomware Encryption Protection - Patch & Asset Management - Email Security - Remote Desktop - Threat Prevention ( DNS based ) - Threat Hunting & Action Center With 9 modules working together seamlessly under one convenient roof, all within one agent and one platform, Heimdal Endpoint Detection and Response grants you access to all the essential cybersecurity layers your business needs to protect itself against both known and unknown online and insider threats. Our state-of-the-art product empowers you to quickly and effortlessly respond to sophisticated malware with stunning accuracy, protecting your digital assets and your reputation in the process as well.
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    Starting Price: $0/month
  • 5
    ESET Endpoint Security
    Uncover the unknown in your network with this EDR solution. This endpoint detection and response tool leverages ESET's multilayered Endpoint Protection Platform. All layers send relevant data to ESET Enterprise Inspector, which analyzes vast amounts of real-time endpoint data. Provides quick analysis and remediation of any security issue in the network. ESET Enterprise Inspector provides a unique behavior and reputation based detection that is fully transparent to security teams. All rules are easily editable via XML to allow fine-tuning. New rules can be created to match the needs of specific enterprise environments, including SIEM integrations. Utilize ESET’s endpoint detection and response tool to easily suppress false alarms by adjusting the sensitivity of detection rules for different computer groups or users. Combine criteria such as file name/path/hash/command line/signer to fine-tune the trigger conditions.
    Starting Price: $38 per user per year
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    Fortinet

    Fortinet

    Fortinet

    Fortinet is a global leader in cybersecurity solutions, known for its comprehensive and integrated approach to safeguarding digital networks, devices, and applications. Founded in 2000, Fortinet provides a wide range of products and services, including firewalls, endpoint protection, intrusion prevention systems, and secure access solutions. At the core of its offerings is the Fortinet Security Fabric, a unified platform that seamlessly integrates security tools to deliver visibility, automation, and real-time threat intelligence across the entire network. Trusted by businesses, governments, and service providers worldwide, Fortinet emphasizes innovation, scalability, and performance, ensuring robust defense against evolving cyber threats while supporting digital transformation and business continuity.
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    Next DLP

    Next DLP

    Next DLP

    Discover risks, educate employees, enforce policies and prevent data loss with Reveal. Your people, users and data are dynamic: constantly changing and moving. In the hybrid world of work people create, manipulate and share data dynamically, across endless channels. The opportunities for data leaks are infinite and your people are the main target— securing your organization starts with securing your people. Reveal Cloud is cloud-native, so it is simple to buy, install, and use. You get automated protection from day 1 with out-of-the-box policies and machine learning, with smart remediation that works even if computers are disconnected from the network. The lightweight agent makes sure your data and employees are protected at all times without slowing you down. Continuous monitoring provides visibility into user behavior, data access, and system use. Security operators can search on file, USB device, connection, browser, application events, and more.
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    ITsMine Beyond DLP
    ITsMine Beyond DLP™ goes beyond traditional Data Loss Prevention (DLP) to protect organizations against all data threats. No policies or endpoint agents needed zero effect on employee productivity, and protection even after data exfiltration. Data loss incidents are becoming more common and more destructive than ever before, whether deliberate or inadvertent or from internal or external factors. Beyond DLP™ is a completely new security approach, that enables organizations to easily track and secure their data wherever it is, within their internal network and beyond. Maintain your high-security standards regardless of whether your data is located in on-prem or cloud-based file systems. Empower employees’ full productivity while controlling the usage and whereabouts of your sensitive data. Hassle-free compliance to data protection regulations, from GDPR, CCPA, PCI to HIPAA, with access control options to sensitive data, data breach detection and clear reporting options.
  • 9
    Netwrix Endpoint Protector
    Netwrix Endpoint Protector is an advanced enterprise-grade Data Loss Prevention (DLP) solution designed to protect sensitive data from unauthorized sharing and malicious extraction from employee endpoints. It offers cross-platform capabilities, supporting Windows, macOS, and Linux operating systems, ensuring comprehensive security across diverse IT environments. The solution provides customizable device control to manage USB and peripheral ports, preventing unauthorized data transfers and mitigating risks associated with data leaks. Additionally, it includes content inspection features that enforce sophisticated policies based on sensitive data categories, keywords, and file types, effectively preventing unauthorized data transfers. Netwrix Endpoint Protector also assists organizations in achieving regulatory compliance with standards such as GDPR, HIPAA, and PCI DSS by securing personally identifiable information, protected health information, and payment card information.
  • 10
    Digital Guardian
    No-compromise data protection means the flexibility to adapt to your needs. Digital Guardian is unique among DLP solutions in its ability to support both a use case-based approach (known data types or user groups) or a data risk discovery approach (identifying unknown use cases). Our risk discovery approach enables you to gain visibility by showing you where sensitive data is located, how it flows in the organization, and where it is put at risk, all without policies. Powered by AWS, Digital Guardian delivers simplified deployment, low overhead, and elastic scalability for increased return on your security spend. Coverage for your Windows, macOS, or Linux operating systems and all your applications, both browser based and native. Our “unknown risk” approach enables you to see where sensitive data is located, how it flows, and where it is put at risk - all without policies. Only Digital Guardian provides content, user, and context-based data discovery and classification.
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    BlackBerry Cyber Suite
    Secure and protect your users and devices, even BYOD laptops and smartphones, with a solution that’s focused on earning trust across any endpoint and continuously validating that trust at every event or transaction. Is your organization equipped with the tools to empower your employees, no matter where they’re working? In a situation where employees may be unable to report to the office, it’s essential that they still have secure access to the data and apps they need, whether they use corporate or personal owned devices. The BlackBerry® Cyber Suite provides complete security, effectively preventing breaches and safeguarding against sophisticated threats with advanced AI. It provides a total Zero Trust solution with coverage across the full spectrum of devices, ownership models, network, apps and people. It continuously authenticates users and dynamically adapts security policies to deliver a Zero Touch experience that improves security with no user interruption.
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    Proofpoint Enterprise Data Loss Prevention (DLP)
    Proofpoint’s Data Loss Prevention solution enables organizations to prevent and manage the risk of sensitive data exposure across email, cloud applications, and endpoints through a unified, cloud-native architecture designed for people-centric protection. It combines advanced content detection (including AI-powered classifiers and optical character recognition), user-behavior analytics, and threat telemetry to identify negligent, compromised, or malicious users and determine intent behind alerts. The platform features a single console that enables triage, investigation, and response across channels; streamlined alert workflows; a lightweight endpoint agent; and support for dynamic policy enforcement, data lineage visualization, and remediation of excess privileges. With this solution, you can detect sensitive file manipulations, uploads to unauthorized destinations, misuse of generative-AI tools, data exfiltration, and abnormal user behaviors while also scaling rapidly.
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    Clearswift Endpoint Data Loss Prevention
    As a vital piece of your IT security strategy, Clearswift Endpoint Data Loss Protection (DLP) solution allows organizations to detect, inspect and secure critical data on endpoints. In one solution, it provides context-aware Data in Use (DIU) policies to control which devices can connect to a corporate network and what information can be transferred. It also executes scheduled Data at Rest (DAR) scans on file systems to audit and manage critical data residing on the network or in the cloud. A lightweight agent, Clearswift Endpoint DLP works behind the scenes to enforce your security and compliance policies and provides continuity even when users are not connected to the network. Flexible and context-aware DIU policies allow organizations to apply rules that either prevent documents containing critical data from being copied to removable media, shared on the network or uploaded to the cloud, or automatically encrypt them before they are transferred.
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