Best Endpoint Protection Software for Mid Size Business
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Compare the Top Endpoint Protection Software for Mid Size Business as of April 2026
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What is Endpoint Protection Software for Mid Size Business?
Endpoint protection software is a software platform that provides the solution to secure endpoints—such as laptops, desktops, smartphones, and tablets—against cyber threats and attacks. These platforms provide real-time monitoring and defense mechanisms to protect devices from malware, ransomware, phishing, and other types of threats. Endpoint protection software typically includes antivirus, anti-malware, firewall, encryption, and intrusion prevention features to prevent unauthorized access and ensure data security. It also allows for centralized management, enabling IT teams to enforce security policies, update software, and monitor the health of all devices in the network. By using endpoint protection software, organizations can safeguard their devices and networks from cyber risks while maintaining compliance with security standards. Compare and read user reviews of the best Endpoint Protection software for Mid Size Business currently available using the table below. This list is updated regularly.
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Guardz
Guardz
Guardz is the unified cybersecurity platform purpose-built for MSPs. We consolidate the essential security controls, including identities, endpoints, email, awareness, and more, into one AI-native framework designed for operational efficiency. Our identity-centric approach connects the dots across vectors, reducing the gaps that siloed tools leave behind so MSPs can see, understand, and act on user risk in real time. Backed by an elite research and threat hunting team, Guardz strengthens detection across environments, turning signals into actionable insights. With 24/7 AI + human-led MDR, Guardz utilizes agentic AI to triage at machine speed while expert analysts validate, mitigate, and guide response, giving MSPs scalable protection without adding headcount. Our mission is simple: give MSPs the scale, confidence, and clarity they need to stay ahead of attackers and deliver protection to every SMB they serve. -
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UTunnel VPN and ZTNA
Secubytes LLC
UTunnel provides Cloud VPN, ZTNA, and Mesh Networking solutions for secure remote access and seamless network connectivity. ACCESS GATEWAY: Our Cloud VPN as a Service offers swift deployment of Cloud or On-Premise VPN servers. It utilizes OpenVPN and IPSec protocols, enables policy-based access control, and lets you deploy a Business VPN network effortlessly. ONE-CLICK ACCESS: A Zero Trust Application Access (ZTAA) solution that simplifies secure access to internal business applications. It allows users to securely access them via web browsers without the need for a client application. MESHCONNECT: This Zero Trust Network Access (ZTNA) and mesh networking solution based on WireGuard enables granular access controls to business network resources and easy creation of secure mesh networks. SITE-TO-SITE VPN: The Access Gateway solution lets you easily set up secure Site-to-Site tunnels (IPSec) between UTunnel's VPN servers and hardware network gateways, firewalls & UTM systems.Starting Price: $6/user/month -
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SafeDNS
SafeDNS
At SafeDNS, we are committed to creating a safer and more secure online environment for SMBs, enterprises, ISPs, MSPs, OEMs, and Education. We have a global footprint, making the internet safer for millions of users in over 60 countries. With years of experience in the field of cybersecurity and DNS filtering, we offer cutting-edge solutions to safeguard your digital life. At present, SafeDNS serves more than 4000 businesses and institutions, and tens of thousands of home users worldwide. We do: -Web content filtering. We help you block all dangerous or unwanted websites such as pornography, violence, child sexual abuse and similar categories. -Malware protection. We also have your back against malicious sites trying to breach user devices either with viruses or information theft intent. -Cloud service. Additionally, we provide you with a cloud filtering service that requires no additional hardware purchase or software installation.Starting Price: $0.9/user/month -
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SentinelOne Singularity
SentinelOne
One intelligent platform. Unprecedented speed. Infinite scale. Singularity™ enables unfettered visibility, industry-leading detection, and autonomous response. Discover the power of AI-powered, enterprise-wide cybersecurity. The world’s leading enterprises use the Singularity platform to prevent, detect, and respond to cyber attacks at machine-speed, greater scale, and higher accuracy across endpoint, cloud, and identity. SentinelOne delivers cutting-edge security with this platform by offering protection against malware, exploits, and scripts. SentinelOne cloud-based platform has been perfected to be innovative compliant with security industry standards, and high-performance whether the work environment is Windows, Mac or Linux. Thanks to constant updating, threat hunting, and behavior AI, the platform is ready for any threat.Starting Price: $45 per user per year -
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Uncover the unknown in your network with this EDR solution. This endpoint detection and response tool leverages ESET's multilayered Endpoint Protection Platform. All layers send relevant data to ESET Enterprise Inspector, which analyzes vast amounts of real-time endpoint data. Provides quick analysis and remediation of any security issue in the network. ESET Enterprise Inspector provides a unique behavior and reputation based detection that is fully transparent to security teams. All rules are easily editable via XML to allow fine-tuning. New rules can be created to match the needs of specific enterprise environments, including SIEM integrations. Utilize ESET’s endpoint detection and response tool to easily suppress false alarms by adjusting the sensitivity of detection rules for different computer groups or users. Combine criteria such as file name/path/hash/command line/signer to fine-tune the trigger conditions.Starting Price: $38 per user per year
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CrowdStrike Falcon
CrowdStrike
CrowdStrike Falcon is a cloud-native cybersecurity platform that provides advanced protection against a wide range of cyber threats, including malware, ransomware, and sophisticated attacks. It leverages artificial intelligence (AI) and machine learning to detect and respond to threats in real time, offering endpoint protection, threat intelligence, and incident response capabilities. The platform uses a lightweight agent that continuously monitors endpoints for signs of malicious activity, providing visibility and protection without significant impact on system performance. Falcon’s cloud-based architecture ensures fast updates, scalability, and rapid threat response across large, distributed environments. Its comprehensive security features help organizations prevent, detect, and mitigate potential cyber risks, making it a powerful tool for modern enterprise cybersecurity. -
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Electric
Electric
Electric is reinventing how businesses manage their IT. Providing real-time IT support to 30,000 users and centralized IT management to over 600 customers, Electric offers companies a 50% reduction in IT spend and standardized security across devices, apps, and networks, whether you're on-site or remote. We have an 100+ person team ready and willing to help with IT support. Once the Electric App is enabled in your Slack workspace or Microsoft Teams tenant, your team will have access to chat with Electric whenever they need help. They'll get a response from a member of our team in 10 minutes or less (our average is 6 minutes). Electric's team of experts is trained to handle a wide range of support needs. From the most basic password reset through device crashes, we've got your team covered. -
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ConnectWise Cybersecurity Management
ConnectWise
Define and Deliver Comprehensive Cybersecurity Services. Security threats continue to grow, and your clients are most likely at risk. Small- to medium-sized businesses (SMBs) are targeted by 64% of all cyberattacks, and 62% of them admit lacking in-house expertise to deal with security issues. Now technology solution providers (TSPs) are a prime target. Enter ConnectWise Cybersecurity Management (formerly ConnectWise Fortify) — the advanced cybersecurity solution you need to deliver the managed detection and response protection your clients require. Whether you’re talking to prospects or clients, we provide you with the right insights and data to support your cybersecurity conversation. From client-facing reports to technical guidance, we reduce the noise by guiding you through what’s really needed to demonstrate the value of enhanced strategy. -
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TrendAI Vision One
Trend Micro
TrendAI Vision One™ is an enterprise cybersecurity platform developed by Trend Micro to secure organizations in the AI era. It provides comprehensive visibility across an organization’s entire digital environment, helping eliminate security blind spots. The platform uses AI-driven analytics to prioritize risks based on business impact and urgency. It enables real-time threat detection, response, and mitigation to protect against evolving cyber threats. TrendAI Vision One™ integrates multiple security functions, including endpoint, cloud, network, and data protection, into a unified platform. It also supports secure AI adoption by safeguarding AI applications and systems from risks like data leakage and prompt injection. Overall, the platform transforms security from reactive defense into proactive risk management for modern enterprises. -
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Carbon Black EDR
Broadcom
Carbon Black Endpoint Detection and Response (EDR) by Broadcom offers a comprehensive solution for detecting, investigating, and responding to cybersecurity threats on endpoints. It utilizes advanced behavioral analysis and machine learning to identify suspicious activities in real time, providing security teams with actionable insights to prevent data breaches and mitigate risks. With its cloud-based architecture, Carbon Black EDR enables continuous monitoring, visibility into endpoint activity, and automated threat response. It’s designed to support organizations of all sizes by improving threat detection, reducing investigation time, and enhancing overall endpoint security. -
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Fortinet
Fortinet
Fortinet is a global leader in cybersecurity solutions, known for its comprehensive and integrated approach to safeguarding digital networks, devices, and applications. Founded in 2000, Fortinet provides a wide range of products and services, including firewalls, endpoint protection, intrusion prevention systems, and secure access solutions. At the core of its offerings is the Fortinet Security Fabric, a unified platform that seamlessly integrates security tools to deliver visibility, automation, and real-time threat intelligence across the entire network. Trusted by businesses, governments, and service providers worldwide, Fortinet emphasizes innovation, scalability, and performance, ensuring robust defense against evolving cyber threats while supporting digital transformation and business continuity. -
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VIPRE Endpoint Security
VIPRE Security Group
VIPRE Endpoint delivers comprehensive defense against today’s sophisticated malware without the complexity of other solutions. We keep your total cost of ownership low while providing advanced security powered by machine learning, real-time behavioral analysis, and a global threat intelligence network. VIPRE combines a modern endpoint solution with time-saving efficiencies, ensuring your organization stays secure and operational. Protecting files, applications, and networks, VIPRE offers complete malware defense. It also helps enforce internet usage policies with granular controls that support employer duty-of-care. Dynamic dashboards provide real-time insights into the status of your endpoint environment, making it easier to monitor and manage security across your organization. Available as a core next-generation AV solution, a full EDR solution, or a combined EDR+MDR solution, we have a package that will work for you.Starting Price: $34/seat/year -
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Shieldoo
Cloudfield
Shieldoo is a next-gen private network for remote connection from anywhere built with a well-known open-source tool called Nebula. The Shieldoo secure network is a collection of nodes, a lighthouse, and an admin center. The user device is a node, the server is a node, the cloud stack is a node, and the LAN access box is a node. Two nodes discover each other through a lighthouse and then connect peer-to-peer. With Shieldoo, you can build a complex security infrastructure which is easy to use. A tailored wizard will guide you through the initial setup, and the usual administration is handled in the admin center. You pay only for users and servers seen in the network that month, and you always get the complete feature set: unlimited admin accounts, SSO, MFA, domain by your choice etc.Starting Price: $0,49 per hour/server/user -
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Cynet empowers MSPs and MSSPs with a comprehensive, fully managed cybersecurity platform that consolidates essential security functions into a single, easy-to-use solution. Cynet simplifies cybersecurity management, reduces operational overhead, and lowers costs by eliminating the need for multiple vendors and complex integrations. The platform provides multi-layered breach protection, offering robust security for endpoints, networks, and SaaS/Cloud environments. Cynet’s advanced automation streamlines incident response, ensuring rapid detection, prevention, and resolution of threats. Additionally, the platform is backed by Cynet’s 24/7 Security Operations Center (SOC), where the expert CyOps team delivers around-the-clock monitoring and support to safeguard all client environments. By partnering with Cynet, You can offer your clients advanced, proactive cybersecurity services while optimizing efficiency. Discover how Cynet can transform your security offerings today.
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Infocyte
Infocyte
The Infocyte Managed Detection and Response platform helps security teams proactively hunt, detect, and respond to cyber threats and vulnerabilities resident within their network—across physical, virtual, and serverless assets. Our MDR platform provides asset and application discovery, automated threat hunting, and on-demand incident response capabilities. Combined, these proactive cyber security practices help organizations control attacker dwell time, reduce overall cyber risk, maintain compliance, and streamline security operations. -
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ConnectWise SIEM
ConnectWise
ConnectWise SIEM (formerly Perch) offers threat detection and response backed by an in-house Security Operations Center (SOC). Defend against business email compromise, account takeovers, and see beyond your network traffic. Our team of threat analysts does all the tedium for you, eliminating the noise and sending only identified and verified treats to action on. Built with multi-tenancy, ConnectWise SIEM helps you keep clients safe with the best threat intel on the market.Starting Price: $10 per month -
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SecurityHQ
SecurityHQ
SecurityHQ is a world leading independent Managed Security Service Provider (MSSP), that detects, and responds to threats, instantly. As your security partner, we alert and act on threats for you. Gain access to an army of analysts that work with you, as an extension of your team, 24/7, 365 days a year. Receive tailored advice and full visibility to ensure peace of mind, with our Global Security Operation Centres. Utilize our award-winning security solutions, knowledge, people, and process capabilities, to accelerate business and reduce risk and overall security costs. Most Popular Services: Managed Detection and Response (MDR) Endpoint Detection and Response (EDR) Managed Extended Detection and Response (XDR) Vulnerability Management Services Managed Firewall Digital Forensics & Incident Response Managed Network Detection and Response (NDR) Penetration Testing CISO as a Service -
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ITsMine Beyond DLP
ITsMine
ITsMine Beyond DLP™ goes beyond traditional Data Loss Prevention (DLP) to protect organizations against all data threats. No policies or endpoint agents needed zero effect on employee productivity, and protection even after data exfiltration. Data loss incidents are becoming more common and more destructive than ever before, whether deliberate or inadvertent or from internal or external factors. Beyond DLP™ is a completely new security approach, that enables organizations to easily track and secure their data wherever it is, within their internal network and beyond. Maintain your high-security standards regardless of whether your data is located in on-prem or cloud-based file systems. Empower employees’ full productivity while controlling the usage and whereabouts of your sensitive data. Hassle-free compliance to data protection regulations, from GDPR, CCPA, PCI to HIPAA, with access control options to sensitive data, data breach detection and clear reporting options. -
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Comodo Dragon Platform
Comodo
Our completely cloud-native framework delivers you zero day protection against undetectable threats while defending your endpoints from known threat signatures. Comodo introduced a new approach to endpoint protection, engineered to solve the issue of legacy security solutions. The Dragon platform delivers the foundation principles for complete next-generation endpoint protection. Easily improve your cybersecurity and performance with the Dragon Platform's lightweight agent delivering artificial intelligence (AI) and Auto Containment to stop all threats. Comodo delivers everything cybersecurity you ever needed to activate breach protection immediate value added from day one. 100% trusted verdict within 45 seconds on 92% of signatures via analysis, and 4 hours SLA on the remaining 8% via human experts. Automatic signature updates that simplifies deployment across your entire environment to lower operational costs. -
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Netacea Bot Management
Netacea
At Netacea we understand bot behaviour better than anyone else, thanks to a pioneering server-side approach to detection and mitigation. Our approach guarantees quick and easy implementation of our technology and enables us to support a wide range of integrations. This ensures comprehensive coverage against malicious bots across your website, mobile apps and APIs, without detriment to your website infrastructure, reliance on hardware or disruptive code changes. We quickly distinguish automated bots from humans to prioritize genuine users, with our team of experts and revolutionary, machine learning powered Intent Analytics™ engine at the heart of the solution. Netacea works hand-in-hand with your in-house security functions from implementation, through to providing accurate detection and empowering you with actionable threat intelligence. -
21
Softchoice
Softchoice
VMware Enterprise Licensing Agreement (ELA). Simplify software asset management (SAM) for VMware. Make the most of your VMware investments. Even the most advanced IT department may struggle to procure, deploy and manage thousands of enterprise VMware assets. Navigating the negotiation and renewal process only adds time and complexity. Without a deep understanding of VMware licensing programs, terms and conditions, it’s easy to fall behind – and risk overspending. A VMware enterprise licensing agreement (ELA) simplifies licensing and reduces costs. With enterprise-wide coverage and 3-year terms, it frees IT resources from time-consuming licensing tasks. Working with Softchoice ensures you get the best value from your ELA. Make the most of your VMware investments. Right-size your SAM strategy. Enterprise software agreements have made it much more cost-effective to acquire the technology that powers your business. -
22
RevBits Endpoint Security
RevBits
Identify, Isolate and Remove Endpoint Threats in Real-Time As an intuitive, high-performance security software, RevBits Endpoint Security blocks the most sophisticated attacks. RevBits Endpoint Security is the only solution available that conducts a three-phase analysis of threats. The feature-rich and comprehensive RevBits Endpoint Detection and Response (EDR) module provide complete control and access to the breached system from anywhere. Ransomware and malware incidents are stories of failed endpoint security. RevBIts Endpoint Security delivers better protection of the endpoint and will deliver organizations a safer network by preventing malware from successful lateral movement in the environment. -
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activeDEFENCE
activereach
From malware to advanced persistent threats (APT) to extortion & internal breaches, threats to your organisation’s infrastructure are unrelenting. Today’s businesses must consider smartphones, tablets, and consumerization of IT, combined with telecommuters, contractors, partners, and business-critical services hosted in the cloud. Security is more important than ever—and far more complex. To defend your information and systems, you need an adaptable, multi-layered defensive strategy that encompasses all the components of your IT environment, from the network to the perimeter, data, applications and endpoints, minimising and managing the weak points and vulnerabilities that expose your organisation to risk. activereach’s end-to-end portfolio of network security solutions can protect your business from advancing threats, enhance network performance, and optimise operational efficiencies. -
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Trellix XDR
Trellix
Introducing the Trellix Platform, a composable XDR ecosystem that adapts to the challenges of your business. The Trellix Platform learns and adapts for living protection while delivering native and open connections and providing expert and embedded support for your team. Keep your organization resilient with adaptive prevention that adjusts and responds in machine time to threats. Customers trust 75M endpoints to Trellix. Maximize business agility through zero trust principles and protect against front-door, side-door, and back-door attacks, all while streamlining policy management. Get comprehensive, non-invasive protection for your cloud-native applications, through secure agile DevOps and visible deployment environments. Our email and collaboration tool security protects against high-volume exposure points and attackers, automating for optimized productivity and enabling secure and agile teamwork. -
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Field Effect
Field Effect
Every business deserves powerful protection from cyber threats. Field Effect’s cybersecurity solutions were purpose-built to prevent, detect and respond to threats for clients of all sizes. We take on the complexity behind the scenes and deliver a solution that’s sophisticated where it matters, and simple everywhere else. Consolidate your tech and eliminate the noise while empowering users of all technical backgrounds to confidently navigate cybersecurity and avoid disruptions. Complexity out, clarity in. -
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Rotate
Rotate
Use the Rotate cloud security platform to secure any business with modular hubs and seamless integrations designed to scale your security needs. Gain greater context on cyberattacks and improve remediation by identifying alerts across all hubs, correlating them, and prioritizing incidents by risk level. Synthesize, consolidate, and manage all hubs in Rotate’s XDR. Use your multi-tenancy control center for vulnerability scans and rapid deployments. Manage unlimited clients through a single pane of glass. Empower your business customers with a complete cybersecurity solution and reduce portfolio risk. Rotate protects all types of organizations in the new world of digital-first work. Get complete cybersecurity for every employee who uses email or brings a device to work. Cyber insurance is essential for any organization at risk of a cyber attack, but coverage can be expensive. Comprehensive protection like the type provided by Rotate can help reduce the overall cost of insurance. -
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Scalable visibility and security analytics across your business. Outsmart emerging threats in your digital business with industry-leading machine learning and behavioral modeling provided by Secure Network Analytics (formerly Stealthwatch). Know who is on the network and what they are doing using telemetry from your network infrastructure. Detect advanced threats and respond to them quickly. Protect critical data with smarter network segmentation. And do it all with an agentless solution that grows with your business. Detect attacks across the dynamic network with high-fidelity alerts enriched with context such as user, device, location, timestamp, and application. Analyze encrypted traffic for threats and compliance, without decryption. Quickly detect unknown malware, insider threats like data exfiltration, policy violations, and other sophisticated attacks using advanced analytics. Store telemetry data for long periods for forensic analysis.
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